Resetting the clock on tooth loss

RegendoGEL™ is a first-in-kind bioative material for vital dental pulp and dentin healing, intended to reset the clock on tooth decay.

CURRENT TREATMENTS

Tooth Decay

Dental caries, commonly known as tooth decay or cavities, is a prevalent oral health condition characterized by the gradual destruction of tooth structure. It is one of the most common chronic diseases worldwide and affects people of all ages.

The process of dental caries begins with the presence of dental plaque, a sticky biofilm that forms on the teeth due to the accumulation of bacteria, food particles, and saliva. The bacteria in plaque metabolize carbohydrates from the food we eat and produce acids as a byproduct. These acids, particularly lactic acid, can demineralize or dissolve the minerals (calcium and phosphate) that make up the tooth enamel, the hard outer layer of the tooth.

Over time, repeated acid attacks weaken the enamel, creating a small hole or cavity. If left untreated, the decay can progress deeper into the tooth, affecting the dentin, which is the softer layer underneath the enamel. The dentin contains tiny tubules that connect to the nerve of the tooth, leading to increased sensitivity, discomfort and infection in the pulp.

Current treatments for pulp exposure and infection involve removing the infected pulp and filling the defect with an inert material. If dental caries progress and cause significant damage to the tooth, treatments such as root canals or extractions may be necessary to prevent further complications. There are currently no products that regenerate the dentin and pulp in a tooth.

THE FUTURE OF DENTAL CARE

Our Solution

RegendoGEL™ is a bioresorbable hydrogel system used to stimulate the tooth’s own healing processes. This is the first and only hydrogel-based product that uses natural tooth derived bioactive molecules to induce dental pulp regeneration. Its biocompatibility, non-inflammatory, and degradable properties reverse the degenerative cycle of tooth decay.

FOR PROVIDERS

Clinician Benefits

  • 1

    Simpler workflow than root canal therapy saves chairside time

  • 2

    Same restoration process keeps good relations with referring dentist

  • 3

    Competitive differentiation

  • 4

    Better patient outcomes

  • 5

    Potential for future procedures on same tooth

FOR PATIENTS

Patient Benefits

RegendoGEL offers several advantages over traditional pulp therapies such as pulpotomy and root canal treatment. It allows for the preservation of the natural tooth structure, eliminates the need for artificial materials, and promotes continued root development in immature teeth.

RegendoGEL has not yet been cleared by the FDA and is not available for sale at this time in the US.